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Examining the Expression of Sickle Cell
Disease During Transcription & Translation

This activity applies the processes of transcription and translation to sickle cell anemia, a disease prominent in African Americans.

Sickle Cell Disease affects 100,000 Americans each year. Healthy red blood cells are round and they move through small blood vessels to carry oxygen to all parts of the body by a protein called hemoglobin. In someone who has SCD, the red blood cells become hard and sticky and look like a C-shaped farm tool called a “sickle”. Sickle Cell Disease affects thousands of people throughout the world but is most common among those whose ancestors come from sub-Saharan Africa.

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